The region is a land of outstanding natural beauty with high mountains, steep valleys and rolling plains. The most remarkable land feature of the region is the Great Rift Valley that runs along the eastern edge of the region and the Omo valley which is the major feature of the region that roughly cuts in to two halves. Along the Omo river valley, a series of highlands complexes are found such as Keffa high lands, Konta highlands, Gofa highlands etc...are the prominent examples
The altitudinal variation of the region extends from the lowest point at-lake Roudolf (Turkana) 376m above sea level to mount Guge of Gamo highlands which is 4200m above sea level.